SPR

I was reading about the Surface Plasmon Resonance, which is one of the optical phenomena of the plasmonic coupling of metal nanoparticles with light, and I thought it would be quite interesting to post some information about it.

Resonant light scattering (RLS), surface-enhanced Raman scattering (SERS) and SPR have tremendous potential for ultrasensitive chemical and biomolecular detection and analysis. Especially, the surface plasmon resonance is important because of it helps to the evaluation of macromolecules, kinetic measurements, analysis of mutant proteins and equilibrium measurements (affinity and enthalpy). We can easily define the SPR as the oscillation of the free electrons at the surface, when treated with a certain frequency (quasi electrons).

Well... I would really like to continue discussing this theme, but I have to go now. I leave more information about.

Asr be kheir

Surface plasmon resonance (SPR) is a phenomenon occuring at metal surfaces (typically gold and silver) when an incident light beam strikes the surface at a particular angle. Depending on the thickness of a molecular layer at the metal surface, the SPR phenomenon results in a graded reduction in intensity of the reflected light. Biomedical applications take advantage
of the exquisite sensitivity of SPR to the refractive index of the medium next to the metal surface, which makes it possible to measure accurately the adsorption of molecules on the metal surface and their eventual interactions with specific ligands.

The last ten years have seen a tremendous development of SPR use in biomedical applications. The technique is applied not only to the measurement in real-time of the kinetics of ligand–receptor interactions and to the screening of lead compounds in
the pharmaceutical industry, but also to the measurement of DNA hybridization, enzyme–substrate interactions, in polyclonal antibody characterization, epitope mapping, protein conformation studies and label-free immunoassays.

Reference::::::

Surface plasmon resonance: principles, methods and applications in biomedical sciences
Patrick Englebienne
Anne Van Hoonacker and Michel Verhas
Free University of Brussels, Department of Nuclear Medicine, Brugmann University Hospital,
Brussels, Belgium

Images::::::

Institut De Physique et Chimie des Materiaux de Strasbourg: JALABERT Rodolfo et WEINMANN Dietmar

Immobilization of Gold Nanoparticles on Silanized Substrate for Sensors Based on Localized Surface Plasmon Resonance(Regular Paper)(March 1, 2007)Shuji Taue, Koji Nishida, Hiroyuki Sakaue, and Takayuki Takahagi.